PRAF2 Antikörper (AA 129-178)

Produktnummer ABIN1533318

Der Kaninchen Polyklonal anti-PRAF2 Antikörper wird verwendet zum Nachweis von PRAF2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für PRAF2 Antikörper (AA 129-178) (ABIN1533318)

Target: PRAF2 (PRA1 Domain Family, Member 2 (PRAF2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRAF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-PRAF2 Antikörper

Bindungsspezifität: AA 129-178

Verwendungszweck: PRAF2 Antibody

Spezifität: PRAF2 Polyclonal Antibody detects endogenous levels of PRAF2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human JM4. AA range:129-178

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu PRAF2

Target: PRAF2 (PRA1 Domain Family, Member 2 (PRAF2))

Andere Bezeichnung: JM4

Hintergrund:

Synonyms: PRAF2, JM4, PRA1 family protein 2

Background: function:May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis.,similarity:Belongs to the PRA1 family.,subunit:Interacts with CCR5 and GDE1.,tissue specificity:Strong expression in the brain, small intestine, lung, spleen, and pancreas as well as in tumor tissues of the breast, colon, lung and ovary, with a weaker expression in normal tissues of the same patient. High expression in neuroblastic tumors. Strongly expressed in Purkinje cells and more moderately in cells of the molecular and the granular layers in the cerebellum. Detected in neuronal cells, but not in non-neuronal cells in the cerebral cortex, hippocampus, and lateral ventricles.,

Gene Name: PRAF2

Protein Name: PRA1 family protein 2

Molekulargewicht: 19 kDa

Gen-ID: 11230

UniProt: O60831

Pathways: Dicarboxylic Acid Transport