Fibrillin 1 Antikörper (AA 2811-2860)

Produktnummer ABIN1533275

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Fibrillin 1 in WB, IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Fibrillin 1 Antikörper (AA 2811-2860) (ABIN1533275)

Target: Fibrillin 1 (FBN1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fibrillin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-Fibrillin 1 Antikörper

Bindungsspezifität: AA 2811-2860

Verwendungszweck: FBN1 Antibody

Spezifität: FBN1 Polyclonal Antibody detects endogenous levels of FBN1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Fibrillin-1. AA range:2811-2860

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Fibrillin 1

Target: Fibrillin 1 (FBN1)

Andere Bezeichnung: Fibrillin-1

Hintergrund:

Synonyms: FBN1, FBN, Fibrillin-1

Background: This gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and nonelastic connective tissue throughout the body. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype, as well as ectopia lentis syndrome, Weill-Marchesani syndrome, Shprintzen-Goldberg syndrome and neonatal progeroid syndrome. [provided by RefSeq, Apr 2016],

Gene Name: FBN1

Protein Name: Fibrillin-1

Molekulargewicht: 312 kDa

Gen-ID: 2200

OMIM: 134797

UniProt: P35555

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interaktom