JUP Antikörper (AA 696-745)

Produktnummer ABIN1533221

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch JUP in WB, IF, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für JUP Antikörper (AA 696-745) (ABIN1533221)

Target: JUP (Junction Plakoglobin (JUP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JUP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA

Produktdetails anti-JUP Antikörper

Bindungsspezifität: AA 696-745

Verwendungszweck: Catenin-γ Antibody

Spezifität: Catenin-γ Polyclonal Antibody detects endogenous levels of Catenin-γ protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Catenin-gamma. AA range:696-745

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu JUP

Target: JUP (Junction Plakoglobin (JUP))

Andere Bezeichnung: Catenin-gamma

Hintergrund:

Synonyms: JUP, CTNNG, DP3, Junction plakoglobin, Catenin gamma, Desmoplakin III, Desmoplakin-3

Background: This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene, however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008],

Gene Name: JUP

Protein Name: Junction plakoglobin

Molekulargewicht: 81 kDa

Gen-ID: 3728

OMIM: 173325

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location