Actin Antikörper (AA 1-50)
Kurzübersicht für Actin Antikörper (AA 1-50) (ABIN1533206)
Target
Alle Actin (ACTA1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-50
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Verwendungszweck
- Actin α1 Antibody
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Spezifität
- Actin α1 Polyclonal Antibody detects endogenous levels of Actin α1 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human Actin-alpha-1. AA range:1-50
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))
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Andere Bezeichnung
- Actin-alpha-1
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Hintergrund
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Synonyms: ACTA1, ACTA, Actin, alpha skeletal muscle, Alpha-actin-1
Background: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008],
Gene Name: ACTA1
Protein Name: Actin alpha skeletal muscle
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Molekulargewicht
- 42 kDa
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Gen-ID
- 58
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OMIM
- 102610
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UniProt
- P68133
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Pathways
- Caspase Kaskade in der Apoptose, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
Target
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