HTRA2 Antikörper (AA 181-230)

Produktnummer ABIN1533174

Der Kaninchen Polyklonal anti-HTRA2 Antikörper wird verwendet zum Nachweis von HTRA2 in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA, IF (p) und IHC (p).

Kurzübersicht für HTRA2 Antikörper (AA 181-230) (ABIN1533174)

Target: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HTRA2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-HTRA2 Antikörper

Bindungsspezifität: AA 181-230

Verwendungszweck: HtrA2 Antibody

Spezifität: HtrA2 Polyclonal Antibody detects endogenous levels of HtrA2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human HtrA2. AA range:181-230

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu HTRA2

Target: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Andere Bezeichnung: HtrA2

Hintergrund:

Synonyms: HTRA2, OMI, PRSS25, Serine protease HTRA2, mitochondrial, High temperature requirement protein A2, HtrA2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI

Background: programmed cell death 1(PDCD1) Homo sapiens This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008],

Gene Name: HTRA2

Protein Name: Serine protease HTRA2 mitochondrial

Molekulargewicht: 48 kDa

OMIM: 168600

UniProt: O43464

Pathways: Positive Regulation of Endopeptidase Activity