Claudin 4 Antikörper (AA 160-209)

Produktnummer ABIN1533162

Der Kaninchen Polyklonal anti-Claudin 4 Antikörper wird verwendet zum Nachweis von Claudin 4 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für Claudin 4 Antikörper (AA 160-209) (ABIN1533162)

Target: Claudin 4 (CLDN4)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Claudin 4 Antikörper

Bindungsspezifität: AA 160-209

Verwendungszweck: Claudin-4 Antibody

Spezifität: Claudin-4 Polyclonal Antibody detects endogenous levels of Claudin-4 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Claudin 4. AA range:160-209

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Claudin 4

Target: Claudin 4 (CLDN4)

Andere Bezeichnung: Claudin 4

Hintergrund:

Synonyms: CLDN4, CPER, CPETR1, WBSCR8, Claudin-4, Clostridium perfringens enterotoxin receptor, CPE-R, CPE-receptor, Williams-Beuren syndrome chromosomal region 8 protein

Background: The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013],

Gene Name: CLDN4

Protein Name: Claudin-4

Molekulargewicht: 22 kDa

Gen-ID: 1364

OMIM: 602909

UniProt: O14493

Pathways: Hepatitis C