CaMKIIalpha/delta Antikörper (AA 256-305)

Produktnummer ABIN1532822

Der Kaninchen Polyklonal anti-CaMKIIalpha/delta Antikörper (ABIN1532822) detektiert spezifisch CaMKIIalpha/delta in IF, WB, IHC und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für CaMKIIalpha/delta Antikörper (AA 256-305) (ABIN1532822)

Target: CaMKIIalpha/delta (CaMK2 a/d) (Calcium/calmodulin-Dependent Protein Kinase II (CaMK2 a/d))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CaMKIIalpha/delta Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-CaMKIIalpha/delta Antikörper

Bindungsspezifität: AA 256-305

Verwendungszweck: CaMKIIα/δ Antibody

Spezifität: CaMKIIα/δ Polyclonal Antibody detects endogenous levels of CaMKIIα/δ protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CaMK2 alpha/delta. AA range:256-305

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CaMKIIalpha/delta

Target: CaMKIIalpha/delta (CaMK2 a/d) (Calcium/calmodulin-Dependent Protein Kinase II (CaMK2 a/d))

Andere Bezeichnung: CaMK2 alpha/delta

Hintergrund:

Synonyms: CAMK2A, CAMKA, KIAA0968, Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2D, CAMKD, Calcium/calmodulin-dependent protein kinase type II subunit delta, CaM kinase II

Background: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],

Gene Name: CAMK2A/CAMK2D

Protein Name: Calcium/calmodulin-dependent protein kinase type II subunit alpha/delta

Molekulargewicht: 54 kDa

Gen-ID: 815, 817

OMIM: 114078

UniProt: Q9UQM7