TCP1 alpha/CCTA Antikörper (pSer395)
Kurzübersicht für TCP1 alpha/CCTA Antikörper (pSer395) (ABIN1532184)
Target
Alle TCP1 alpha/CCTA (TCP1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 361-410, pSer395
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Verwendungszweck
- p63 (phospho Ser395) Antibody
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Spezifität
- Phospho-p63 (S395) Polyclonal Antibody detects endogenous levels of p63 protein only when phosphorylated at S395.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human p63 around the phosphorylation site of Ser395. AA range:361-410
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))
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Andere Bezeichnung
- p63
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Hintergrund
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Synonyms: TP63, KET, P63, P73H, P73L, TP73L, Tumor protein 63, p63, Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, Transformation-related protein 63, TP63, Tumor protein p73-like, p73L, p40, p51
Background: tumor protein p63(TP63) Homo sapiens This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3), split-hand/foot malformation 4 (SHFM4), ankyloblepharon-ectodermal defects-cleft lip/palate, ADULT syndrome (acro-dermato-ungual-lacrim
Gene Name: TP63
Protein Name: Tumor protein 63
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Molekulargewicht
- 76 kDa
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Gen-ID
- 8626
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OMIM
- 103285
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UniProt
- Q9H3D4
Target
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