Claudin 5 Antikörper (pTyr217)

Produktnummer ABIN1532132

Der Kaninchen Polyklonal anti-Claudin 5 Antikörper (ABIN1532132) detektiert spezifisch Claudin 5 in IHC, WB, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für Claudin 5 Antikörper (pTyr217) (ABIN1532132)

Target: Claudin 5 (CLDN5)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-Claudin 5 Antikörper

Bindungsspezifität: AA 169-218, pTyr217

Verwendungszweck: Claudin-5 (phospho Tyr217) Antibody

Spezifität: Phospho-Claudin-5 (Y217) Polyclonal Antibody detects endogenous levels of Claudin-5 protein only when phosphorylated at Y217.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Claudin 5 around the phosphorylation site of Tyr217. AA range:169-218

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Claudin 5

Target: Claudin 5 (CLDN5)

Andere Bezeichnung: Claudin 5

Hintergrund:

Synonyms: CLDN5, AWAL, TMVCF, Claudin-5, Transmembrane protein deleted in VCFS, TMDVCF

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2008],

Gene Name: CLDN5

Protein Name: Claudin-5

Molekulargewicht: 23 kDa

Gen-ID: 7122

OMIM: 602101

UniProt: O00501

Pathways: Hepatitis C