HRH1 Antikörper (pSer398)

Produktnummer ABIN1531653

Der Kaninchen Polyklonal anti-HRH1 Antikörper (ABIN1531653) detektiert spezifisch HRH1 in ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für HRH1 Antikörper (pSer398) (ABIN1531653)

Target: HRH1 (Histamine Receptor H1 (HRH1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HRH1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Produktdetails anti-HRH1 Antikörper

Bindungsspezifität: AA 364-413, pSer398

Verwendungszweck: Histamine H1 Receptor (phospho Ser398) Antibody

Spezifität: Phospho-Histamine H1 Receptor (S398) Polyclonal Antibody detects endogenous levels of Histamine H1 Receptor protein only when phosphorylated at S398.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Histamine H1 Receptor around the phosphorylation site of Ser398. AA range:364-413

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu HRH1

Target: HRH1 (Histamine Receptor H1 (HRH1))

Andere Bezeichnung: Histamine H1 Receptor

Hintergrund:

Synonyms: HRH1, Histamine H1 receptor, H1R, HH1R

Background: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4.The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. It has been associated with multiple processes, including memory and learning, circadian rhythm, and thermoregulation. It is also known to contribute to the pathophysiology of allergic diseases such as atopic dermatitis, asthma, anaphylaxis and allergic rhinitis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by Ref

Gene Name: HRH1

Protein Name: Histamine H1 receptor

Molekulargewicht: 55 kDa

Gen-ID: 3269

OMIM: 600167

UniProt: P35367

Pathways: Regulation of Carbohydrate Metabolic Process