KRT8 Antikörper (pSer432)

Produktnummer ABIN1531568

Der Kaninchen Polyklonal anti-KRT8 Antikörper wird verwendet zum Nachweis von KRT8 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, IHC, IF und ELISA.

Kurzübersicht für KRT8 Antikörper (pSer432) (ABIN1531568)

Target: KRT8 (Keratin 8 (KRT8))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KRT8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Produktdetails anti-KRT8 Antikörper

Bindungsspezifität: AA 401-450, pSer432

Verwendungszweck: Cytokeratin 8 (phospho Ser432) Antibody

Spezifität: Phospho-Cytokeratin 8 (S432) Polyclonal Antibody detects endogenous levels of Cytokeratin 8 protein only when phosphorylated at S432.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Keratin 8 around the phosphorylation site of Ser432. AA range:401-450

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu KRT8

Target: KRT8 (Keratin 8 (KRT8))

Andere Bezeichnung: Keratin 8

Hintergrund:

Synonyms: KRT8, CYK8, Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, Type-II keratin Kb8

Background: keratin 8(KRT8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],

Gene Name: KRT8

Protein Name: Keratin type II cytoskeletal 8

Molekulargewicht: 53 kDa

Gen-ID: 3856

OMIM: 148060

UniProt: P05787