CXCR4 Antikörper (pSer339)

Produktnummer ABIN1531564

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CXCR4 in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte und Affe.

Kurzübersicht für CXCR4 Antikörper (pSer339) (ABIN1531564)

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCR4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CXCR4 Antikörper

Bindungsspezifität: AA 303-352, pSer339

Verwendungszweck: Fusin (phospho Ser339) Antibody

Spezifität: Phospho-Fusin (S339) Polyclonal Antibody detects endogenous levels of Fusin protein only when phosphorylated at S339.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CXCR4 around the phosphorylation site of Ser339. AA range:303-352

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CXCR4

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Andere Bezeichnung: CXCR4

Hintergrund:

Synonyms: CXCR4, C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, FB22, Fusin, HM89, LCR1, Leukocyte-derived seven transmembrane domain receptor, LESTR, NPYRL, Stromal cell-derived factor 1 receptor, SDF-1 receptor, CD antigen CD184

Background: C-X-C motif chemokine receptor 4(CXCR4) Homo sapiens This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

Gene Name: CXCR4

Protein Name: C-X-C chemokine receptor type 4

Molekulargewicht: 39 kDa

Gen-ID: 7852

OMIM: 162643

UniProt: P61073

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events