PKC mu Antikörper (pTyr463)

Produktnummer ABIN1531512

Der Kaninchen Polyklonal anti-PKC mu Antikörper (ABIN1531512) detektiert spezifisch PKC mu in WB, ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für PKC mu Antikörper (pTyr463) (ABIN1531512)

Target: PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKC mu Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-PKC mu Antikörper

Bindungsspezifität: AA 429-478, pTyr463

Verwendungszweck: PKD1 (phospho Tyr463) Antibody

Spezifität: Phospho-PKD1 (Y463) Polyclonal Antibody detects endogenous levels of PKD1 protein only when phosphorylated at Y463.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PKD1/PKC mu around the phosphorylation site of Tyr463. AA range:429-478

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu PKC mu

Target: PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))

Andere Bezeichnung: PKD1/PKC mu

Hintergrund:

Synonyms: PRKD1, PKD, PKD1, PRKCM, Serine/threonine-protein kinase D1, Protein kinase C mu type, Protein kinase D, nPKC-D1, nPKC-mu

Background: PRKD1 is a serine/threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion (summary by Eiseler et al., 2009 [PubMed 19329994]).[supplied by OMIM, Nov 2010],

Gene Name: PRKD1

Protein Name: Serine/threonine-protein kinase D1

Molekulargewicht: 101 kDa

Gen-ID: 5587

OMIM: 605435

UniProt: Q15139

Pathways: Myometrial Relaxation and Contraction