BCAR1 Antikörper (pTyr249)
Kurzübersicht für BCAR1 Antikörper (pTyr249) (ABIN1531453)
Target
Alle BCAR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 215-264, pTyr249
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Spezifität
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p130 Cas (Phospho-Tyr249) Antibody detects endogenous levels of p130 Cas only when phosphorylated at Tyr249.
PhosphorylationH:Y249 M:Y253 R:Y347
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Aufreinigung
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human p130 Cas around the phosphorylation site of Tyr249.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000
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Kommentare
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Unigene-Number: Hs.479747 (NCBI Gene Symbol: BCAR1)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable at -20°C for at least 1 year.
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Haltbarkeit
- 12 months
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- BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))
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Andere Bezeichnung
- p130 Cas
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Hintergrund
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Synonyms: BCA1, BCAR1, Breast cancer anti-estrogen resistance 1 protein, CAS, CRK-associated substrate, CRKAS
NCBI Gene Symbol: BCAR1
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Molekulargewicht
- 93 kDa
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Gen-ID
- 9564
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OMIM
- 602941
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UniProt
- P56945
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Pathways
- EGFR Signaling Pathway, Neurotrophin Signalübertragung, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
Target
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