BCAR1 Antikörper (pTyr165)

Produktnummer ABIN1531452

Produktdetails anti-BCAR1 Antikörper

Target: BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))

Bindungsspezifität: AA 131-180, pTyr165

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCAR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität:

p130 Cas (Phospho-Tyr165) Antibody detects endogenous levels of p130 Cas only when phosphorylated at Tyr165.

PhosphorylationH:Y165 M:Y169 R:Y263

Aufreinigung: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human p130 Cas around the phosphorylation site of Tyr165.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000

Kommentare:

Unigene-Number: Hs.479747 (NCBI Gene Symbol: BCAR1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable at -20°C for at least 1 year.

Haltbarkeit: 12 months

Details zu BCAR1

Target: BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))

Andere Bezeichnung: p130 Cas (BCAR1 Produkte)

Hintergrund:

Synonyms: BCA1, BCAR1, Breast cancer anti-estrogen resistance 1 protein, CAS, CRK-associated substrate, CRKAS

NCBI Gene Symbol: BCAR1

Molekulargewicht: 93 kDa

Gen-ID: 9564

OMIM: 602941

UniProt: P56945

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling