Fc gamma RII (CD32) (AA 258-307), (pTyr292) Antikörper

Produktnummer ABIN1531425

Der Kaninchen Polyklonal anti-Fc gamma RII Antikörper (ABIN1531425) detektiert spezifisch Fc gamma RII in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für Fc gamma RII (CD32) (AA 258-307), (pTyr292) Antikörper (ABIN1531425)

Target: Fc gamma RII (CD32)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails

Bindungsspezifität: AA 258-307, pTyr292

Verwendungszweck: CD32 (phospho Tyr292) Antibody

Spezifität: Phospho-CD32 (Y292) Polyclonal Antibody detects endogenous levels of CD32 protein only when phosphorylated at Y292.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CD32 around the phosphorylation site of Tyr292. AA range:258-307

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Antigendetails

Target: Fc gamma RII (CD32)

Andere Bezeichnung: CD32

Hintergrund:

Synonyms: FCGR2B, CD32, FCG2, IGFR2, Low affinity immunoglobulin gamma Fc region receptor II-b, IgG Fc receptor II-b, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, CD antigen CD32

Background: The Fc fragment of IgG receptor IIb encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

Gene Name: FCGR2B

Protein Name: Low affinity immunoglobulin gamma Fc region receptor II-b

Molekulargewicht: 34 kDa

Gen-ID: 2213

OMIM: 604590

UniProt: P31994