OPRK1 Antikörper (pSer369)

Produktnummer ABIN1531292

Der Kaninchen Polyklonal anti-OPRK1 Antikörper (ABIN1531292) detektiert spezifisch OPRK1 in WB, ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Ratte und Maus.

Kurzübersicht für OPRK1 Antikörper (pSer369) (ABIN1531292)

Target: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OPRK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-OPRK1 Antikörper

Bindungsspezifität: AA 331-380, pSer369

Verwendungszweck: KOR-1 (phospho Ser369) Antibody

Spezifität: Phospho-KOR-1 (S369) Polyclonal Antibody detects endogenous levels of KOR-1 protein only when phosphorylated at S369.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from mouse KOR-1 around the phosphorylation site of Ser369. AA range:331-380

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu OPRK1

Target: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Andere Bezeichnung: KOR-1

Hintergrund:

Synonyms: OPRK1, OPRK, Kappa-type opioid receptor, K-OR-1, KOR-1

Background: Endogenous opioid peptides and opiates, like morphine, transmit their pharmacological effects through membrane bound opioid receptors. Pharmacological studies and molecular cloning have led to the identification of three different types of opioid receptor, mu-type, delta-type and kappa-type, also designated MOR-1, DOR-1 and KOR-1, respectively. MOR-1 is a receptor for beta-endorphin, DOR-1 is a receptor for enkephalins, and KOR-1 is a receptor for dynorphins.The three opioid receptor types are highly homologous and belong to the superfamily of G-protein-coupled receptors. Opioid receptors have been shown to modulate a range of brain functions, including instinctive behavior and emotions. This regulation is thought to involve the inhibition of neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.

Gene Name: OPRK1

Protein Name: Kappa-type opioid receptor

Molekulargewicht: 42 kDa

UniProt: P41145