GR (AA 201-250), (pSer226) Antikörper

Produktnummer ABIN1531277

Produktdetails

Target: GR

Bindungsspezifität: AA 201-250, pSer226

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität:

GR (Phospho-Ser226) Antibody detects endogenous levels of GR only when phosphorylated at Ser226.

PhosphorylationH:S226 M:S234 R:S246

Aufreinigung: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GR around the phosphorylation site of Ser226.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000

Kommentare:

Unigene-Number: Hs.122926 (NCBI Gene Symbol: GCR)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable at -20°C for at least 1 year.

Haltbarkeit: 12 months

Referenzen

Allan, Goggin, Caldwell: "Prenatal alcohol exposure modifies glucocorticoid receptor subcellular distribution in the medial prefrontal cortex and impairs frontal cortex-dependent learning." in: PLoS ONE, Vol. 9, Issue 4, pp. e96200, (2014) (PubMed).

Antigendetails

Target: GR

Hintergrund:

Synonyms: GCR, GRL, GRL1, NR3C1, glucocorticoid receptor

NCBI Gene Symbol: GCR

Molekulargewicht: 85 kDa

Gen-ID: 2908

OMIM: 138040

UniProt: P04150