WFS1 Antikörper (AA 1-285)

Produktnummer ABIN1513689

Produktdetails anti-WFS1 Antikörper

Target: WFS1 (Wolfram Syndrome 1 (WFS1))

Bindungsspezifität: AA 1-285

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WFS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: MDSNTAPLGP SCPQPPPAPQ PQARSRLNAT ASLEQERSER PRAPGPQAGP GPGVRDAAAP AEPQAQHTRS RERADGTGPT KGDMEIPFEE VLERAKAGDP KAQTEVGKHY LQLAGDTDEE LNSCTAVDWL VLAAKQGRRE AVKLLRRCLA DRRGITSENE REVRQLSSET DLERAVRKAA LVMYWKLNPK KKKQVAVAEL LENVGQVNEH DGGAQPGPVP KSLQKQRRML ERLVSSESKN YIALDDFVEI TKKYAKGVIP SSLFLQDDED DDELAGKSPE DLPLR

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-285 of human WFS1 (NP_001139325.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu WFS1

Target: WFS1 (Wolfram Syndrome 1 (WFS1))

Andere Bezeichnung: WFS1 (WFS1 Produkte)

Synonyme: WFRS antikoerper, WFS antikoerper, WFSL antikoerper, CG4917 antikoerper, Dmel\\CG4917 antikoerper, GB15257 antikoerper, WFS1 antikoerper, AI481085 antikoerper, wolframin antikoerper, wfs1 antikoerper, wolframin ER transmembrane glycoprotein antikoerper, wolfram syndrome 1 antikoerper, wolframin antikoerper, Wolfram syndrome 1 (wolframin) L homeolog antikoerper, Wfs1 antikoerper, WFS1 antikoerper, wfs1 antikoerper, LOC552818 antikoerper, CpipJ_CPIJ013087 antikoerper, wfs1.L antikoerper

Hintergrund: This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene.,WFS1,CTRCT41,WFRS,WFS,WFSL,wolframin,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Insulin and insulin-like,Endocrine & Metabolism,Endocrine and metabolic diseases,Metabolic disorders,Neuroscience,WFS1

Molekulargewicht: 100 kDa

Gen-ID: 7466

UniProt: O76024

Pathways: Sensory Perception of Sound, Carbohydrate Homeostasis, ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interaktom