CD63 Antikörper
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- Target Alle CD63 Antikörper anzeigen
- CD63
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD63 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB)
- Spezifität
- This antibody reacts with mouse CD63.
- Aufreinigung
- Protein G agarose
- Klon
- R5G2
- Isotyp
- IgG2b
- Top Product
- Discover our top product CD63 Primärantikörper
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anti-CD63 (CD63) (AA 120-175) antibody
CD63 Reaktivität: Human, Maus, Ratte, Affe, Hund FACS, WB, IHC, IF Wirt: Ziege Polyclonal unconjugated
anti-CD63 (CD63) antibodyCD63 Reaktivität: Human FACS, IHC (p), IP, ICC Wirt: Maus Monoclonal MEM-259 unconjugated
anti-CD63 (CD63) antibody (Biotin)CD63 Reaktivität: Human FACS, IHC (p), IP, ICC Wirt: Maus Monoclonal MEM-259 Biotin
anti-CD63 (CD63) antibody (APC)CD63 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-259 APC
anti-CD63 (CD63) (AA 163-190), (C-Term) antibodyCD63 Reaktivität: Human FACS, WB, IHC (p) Wirt: Kaninchen Polyclonal RB26813 unconjugated
anti-CD63 (CD63) (AA 103-203) antibodyCD63 Reaktivität: Human FACS, WB, IHC, IF, ELISA Wirt: Maus Monoclonal 10F11E6 unconjugated
anti-CD63 (CD63) (AA 103-203) antibodyCD63 Reaktivität: Human FACS, WB, IHC, IF, ELISA Wirt: Maus Monoclonal 1H1E11 unconjugated
anti-CD63 (CD63) antibody (PerCP)CD63 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-259 PerCP
anti-CD63 (CD63) antibody (PE)CD63 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-259 PE
anti-CD63 (CD63) (AA 103-203) antibodyCD63 Reaktivität: Human FACS, IHC, ELISA Wirt: Maus Monoclonal 1E8D4 unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
- Konservierungsmittel
- Without preservative
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- Target
- CD63
- Andere Bezeichnung
- CD63 (CD63 Produkte)
- Hintergrund
- CD63 is not only expressed on activated platelets, but also activated monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and translocated to cell surface upon various stimuli. The membrane of lytic granules in CTLs contains CD63/LAMP-3 and other lysosomal-associated glycoproteins (LAMPs) such as CD107a/LAMP-1 and CD107b/LAMP-2. LAMPs have b een observed on the cell surface as a result of degranulation. CD63 belongs to a member of the tetraspanin transmembrane-protein (TM4) superfamily, which includes CD9, CD37, CD53, CD81, CD82, CD151 and CD231. Several members of this family form noncovalent associations with integrins, particularly ß 1 integrins (CD29), and modulate cellular adhesion properties. CD63 has a tyrosine-based internalization motif in the cytoplasmic C-terminal tail and interacts with adaptor protein complexes such as AP-2 and AP-3. Because AP-2 and AP-3 are involved in facilitating the clathrin-mediated endocytosis, CD63 could be directly involved in the internalization of its membrane protein partners.Synonyms: Granulophysin, ME491, MLA1, Melanoma-associated antigen ME491, OMA81H, Ocular melanoma-associated antigen, TSPAN30, Tetraspanin-30
- Gen-ID
- 12512
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