NPY Antikörper (AA 45-94)

Produktnummer ABIN1453677

Der Kaninchen Polyklonal anti-NPY Antikörper (ABIN1453677) detektiert spezifisch NPY in WB, IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für NPY Antikörper (AA 45-94) (ABIN1453677)

Target: NPY (Neuropeptide Y (NPY))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NPY Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-NPY Antikörper

Bindungsspezifität: AA 45-94

Verwendungszweck: NPY Antibody

Spezifität: NPY Polyclonal Antibody detects endogenous levels of NPY protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human NPY. AA range:45-94

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-500,WB 1:500-2000,ELISA 1:5000-20000. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu NPY

Target: NPY (Neuropeptide Y (NPY))

Andere Bezeichnung: NPY

Hintergrund:

Synonyms: NPY, Pro-neuropeptide Y

Background: This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014],

Gene Name: NPY

Protein Name: Pro-neuropeptide Y

Molekulargewicht: 10 kDa

Gen-ID: 4852

OMIM: 162640

UniProt: P01303

Pathways: Feeding Behaviour