BIRC7 Antikörper (AA 162-211)

Produktnummer ABIN1453581

Der Kaninchen Polyklonal anti-BIRC7 Antikörper (ABIN1453581) detektiert spezifisch BIRC7 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für BIRC7 Antikörper (AA 162-211) (ABIN1453581)

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BIRC7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-BIRC7 Antikörper

Bindungsspezifität: AA 162-211

Verwendungszweck: ML-IAP Antibody

Spezifität: ML-IAP Polyclonal Antibody detects endogenous levels of ML-IAP protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human ML-IAP. AA range:162-211

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu BIRC7

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Andere Bezeichnung: ML-IAP

Hintergrund:

Synonyms: BIRC7, KIAP, LIVIN, MLIAP, RNF50, Baculoviral IAP repeat-containing protein 7, Kidney inhibitor of apoptosis protein, KIAP, Livin, Melanoma inhibitor of apoptosis protein, ML-IAP, RING finger protein 50

Background: This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jul 2013],

Gene Name: BIRC7

Protein Name: Baculoviral IAP repeat-containing protein 7

Molekulargewicht: 32 kDa

Gen-ID: 79444

OMIM: 605737

UniProt: Q96CA5