MFN2 Antikörper (AA 354-403)

Produktnummer ABIN1453569

Der Kaninchen Polyklonal anti-MFN2 Antikörper (ABIN1453569) detektiert spezifisch MFN2 in WB, IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für MFN2 Antikörper (AA 354-403) (ABIN1453569)

Target: MFN2 (Mitofusin 2 (MFN2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MFN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-MFN2 Antikörper

Bindungsspezifität: AA 354-403

Verwendungszweck: Mfn2 Antibody

Spezifität: Mfn2 Polyclonal Antibody detects endogenous levels of Mfn2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human Mfn2. AA range:354-403

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu MFN2

Target: MFN2 (Mitofusin 2 (MFN2))

Andere Bezeichnung: Mfn2

Hintergrund:

Synonyms: MFN2, CPRP1, KIAA0214, Mitofusin-2, Transmembrane GTPase MFN2

Background: This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008],

Gene Name: MFN2

Protein Name: Mitofusin-2

Molekulargewicht: 86 kDa

Gen-ID: 9927

OMIM: 608507

UniProt: O95140

Pathways: Skeletal Muscle Fiber Development