Fatty Acid Synthase Antikörper (AA 1478-1527)
Kurzübersicht für Fatty Acid Synthase Antikörper (AA 1478-1527) (ABIN1453278)
Target
Alle Fatty Acid Synthase (FASN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1478-1527
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Verwendungszweck
- Fatty Acid Synthase Antibody
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Spezifität
- Fatty Acid Synthase Polyclonal Antibody detects endogenous levels of Fatty Acid Synthase protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- The antiserum was produced against synthesized peptide derived from human Fatty Acid Synthase. AA range:1478-1527
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Isotyp
- IgG
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Applikationshinweise
- IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- Fatty Acid Synthase (FASN)
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Andere Bezeichnung
- Fatty Acid Synthase
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Hintergrund
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Synonyms: FASN, FAS, Fatty acid synthase
Background: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008],
Gene Name: FASN
Protein Name: Fatty acid synthase
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Molekulargewicht
- 273 kDa
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Gen-ID
- 2194
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OMIM
- 600212
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UniProt
- P49327
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Pathways
- AMPK Signaling
Target
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