ITIH2 Antikörper (Cleaved-Asp702)

Produktnummer ABIN1452255

Der Kaninchen Polyklonal anti-ITIH2 Antikörper (ABIN1452255) detektiert spezifisch ITIH2 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für ITIH2 Antikörper (Cleaved-Asp702) (ABIN1452255)

Target: ITIH2 (Inter-alpha Globulin Inhibitor H2 Polypeptide (ITIH2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITIH2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ITIH2 Antikörper

Bindungsspezifität: AA 653-702, Cleaved-Asp702

Verwendungszweck: Cleaved-ITI-H2 (D702) Antibody

Spezifität: Cleaved-ITI-H2 (D702) Polyclonal Antibody detects endogenous levels of fragment of activated ITI-H2 protein resulting from cleavage adjacent to D702.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human ITIH2. AA range:653-702

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu ITIH2

Target: ITIH2 (Inter-alpha Globulin Inhibitor H2 Polypeptide (ITIH2))

Andere Bezeichnung: ITIH2

Hintergrund:

Synonyms: ITIH2, IGHEP2, Inter-alpha-trypsin inhibitor heavy chain H2, ITI heavy chain H2, ITI-HC2, Inter-alpha-inhibitor heavy chain 2, Inter-alpha-trypsin inhibitor complex component II, Serum-derived hyaluronan-associated protein, SHAP

Background: The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al., 1987 [PubMed 2446322], Himmelfarb et al., 2004 [PubMed 14744536]).[supplied by OMIM, Nov 2009],

Gene Name: ITIH2

Protein Name: Inter-alpha-trypsin inhibitor heavy chain H2

Molekulargewicht: 106 kDa

Gen-ID: 3698

OMIM: 146640

UniProt: P19823

Pathways: Glycosaminoglycan Metabolic Process