NRF1 Antikörper (AA 221-270)

Produktnummer ABIN1452021

Der Kaninchen Polyklonal anti-NRF1 Antikörper (ABIN1452021) detektiert spezifisch NRF1 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte und Rind (Kuh).

Kurzübersicht für NRF1 Antikörper (AA 221-270) (ABIN1452021)

Target: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NRF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-NRF1 Antikörper

Bindungsspezifität: AA 221-270

Verwendungszweck: NRF-1 Antibody

Spezifität: NRF-1 Polyclonal Antibody detects endogenous levels of NRF-1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human NRF1. AA range:221-270

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu NRF1

Target: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Andere Bezeichnung: NRF1

Hintergrund:

Synonyms: NRF1; Nuclear respiratory factor 1; NRF-1; Alpha palindromic-binding protein; Alpha-pal

Background: This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014],

Gene Name: NRF1

Protein Name: Nuclear respiratory factor 1

Molekulargewicht: 53 kDa

Gen-ID: 4899

OMIM: 600879

UniProt: Q16656

Pathways: Regulation of Lipid Metabolism by PPARalpha