SRCIN1 Antikörper (AA 811-860)

Produktnummer ABIN1451982

Der Kaninchen Polyklonal anti-SRCIN1 Antikörper (ABIN1451982) detektiert spezifisch SRCIN1 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für SRCIN1 Antikörper (AA 811-860) (ABIN1451982)

Target: SRCIN1 (SRC Kinase Signaling Inhibitor 1 (SRCIN1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRCIN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SRCIN1 Antikörper

Bindungsspezifität: AA 811-860

Verwendungszweck: p140Cap Antibody

Spezifität: P140Cap Polyclonal Antibody detects endogenous levels of p140Cap protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human SNIP. AA range:811-860

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu SRCIN1

Target: SRCIN1 (SRC Kinase Signaling Inhibitor 1 (SRCIN1))

Andere Bezeichnung: SNIP

Hintergrund:

Synonyms: SRCIN1, KIAA1684, P140, SRC kinase signaling inhibitor 1, SNAP-25-interacting protein, SNIP, p130Cas-associated protein, p140Cap

Background: function:Delays the onset of cell spreading in the early stages of cell adhesion to fibronectin. Also involved in calcium-dependent exocytosis from PC12 cells.,PTM:Tyrosine-phosphorylated in response to EGF and to cell adhesion to integrin ligands.,similarity:Belongs to the p140Cap family.,subcellular location:Localized to the perinuclear region, lamellopodia, cortical actin and actin stress fibers but not to focal adhesions.,subunit:Interacts with the N-terminal coiled-coil region of SNAP25 (By similarity). Interacts with BCAR1/p130Cas through its C-terminal domain.,

Gene Name: SRCIN1

Protein Name: SRC kinase signaling inhibitor 1

Molekulargewicht: 112 kDa

Gen-ID: 80725

OMIM: 610786

UniProt: Q9C0H9