TAO Kinase 3 Antikörper (AA 531-580)
Kurzübersicht für TAO Kinase 3 Antikörper (AA 531-580) (ABIN1451898)
Target
Alle TAO Kinase 3 (TAOK3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 531-580
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Verwendungszweck
- JIK Antibody
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Spezifität
- JIK Polyclonal Antibody detects endogenous levels of JIK protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- The antiserum was produced against synthesized peptide derived from human TAOK3. AA range:531-580
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- TAO Kinase 3 (TAOK3)
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Andere Bezeichnung
- TAOK3
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Hintergrund
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Synonyms: TAOK3, DPK, JIK, KDS, MAP3K18, Serine/threonine-protein kinase TAO3, Cutaneous T-cell lymphoma-associated antigen HD-CL-09, CTCL-associated antigen HD-CL-09, Dendritic cell-derived protein kinase, JNK/SAPK-inhibitory kinase, Jun kinase-inhi
Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK.,PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Also localized to the peripheral cell membrane.,subunit:Self-associates.,tissue specificity:Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.,
Gene Name: TAOK3
Protein Name: Serine/threonine-protein kinase TAO3
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Molekulargewicht
- 105 kDa
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Gen-ID
- 51347
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UniProt
- Q9H2K8
Target
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