MNT Antikörper (AA 315-364)

Produktnummer ABIN1451880

Der Kaninchen Polyklonal anti-MNT Antikörper (ABIN1451880) detektiert spezifisch MNT in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für MNT Antikörper (AA 315-364) (ABIN1451880)

Target: MNT (MNT, MAX Dimerization Protein (MNT))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MNT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-MNT Antikörper

Bindungsspezifität: AA 315-364

Verwendungszweck: MNT Antibody

Spezifität: MNT Polyclonal Antibody detects endogenous levels of MNT protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human MNT. AA range:315-364

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu MNT

Target: MNT (MNT, MAX Dimerization Protein (MNT))

Andere Bezeichnung: MNT

Hintergrund:

Synonyms: MNT, BHLHD3, ROX, Max-binding protein MNT, Class D basic helix-loop-helix protein 3, bHLHd3, Myc antagonist MNT, Protein ROX

Background: The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression.This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. [provided by RefSeq, Jul 2008],

Gene Name: MNT

Protein Name: Max-binding protein MNT

Molekulargewicht: 62 kDa

Gen-ID: 4335

OMIM: 603039

UniProt: Q99583

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation