Repetin Antikörper (AA 648-697)

Produktnummer ABIN1451544

Der Kaninchen Polyklonal anti-Repetin Antikörper (ABIN1451544) detektiert spezifisch Repetin in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Repetin Antikörper (AA 648-697) (ABIN1451544)

Target: Repetin (RPTN)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Repetin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Repetin Antikörper

Bindungsspezifität: AA 648-697

Verwendungszweck: Repetin Antibody

Spezifität: Repetin Polyclonal Antibody detects endogenous levels of Repetin protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human RPTN. AA range:648-697

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Repetin

Target: Repetin (RPTN)

Andere Bezeichnung: RPTN

Hintergrund:

Synonyms: RPTN, Repetin

Background: domain:Can be divided into a N-terminal domain with significant homology to S100-like calcium-binding proteins, a central domain containing a series of short tandem repeats, and two flanking segments with low homology to the consensus sequences of the central repeats.,function:Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Potential substrate of transglutaminase. Some arginines are probably converted to citrullines by peptidylarginine deimidase.,similarity:Belongs to the S100-fused protein family.,similarity:Contains 2 EF-hand domains.,tissue specificity:Expression is scattered in the normal epidermis but strong in the acrosyringium, the inner hair root sheat and in the filiform papilli of the tongue.,

Gene Name: RPTN

Protein Name: Repetin

Molekulargewicht: 90 kDa

Gen-ID: 126638

UniProt: Q6XPR3