Plakophilin 4 Antikörper (AA 185-234)

Produktnummer ABIN1451430

Der Kaninchen Polyklonal anti-Plakophilin 4 Antikörper (ABIN1451430) detektiert spezifisch Plakophilin 4 in WB, IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für Plakophilin 4 Antikörper (AA 185-234) (ABIN1451430)

Target: Plakophilin 4 (PKP4)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Plakophilin 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-Plakophilin 4 Antikörper

Bindungsspezifität: AA 185-234

Verwendungszweck: Plakophilin 4 Antibody

Spezifität: Plakophilin 4 Polyclonal Antibody detects endogenous levels of Plakophilin 4 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human PKP4. AA range:185-234

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Plakophilin 4

Target: Plakophilin 4 (PKP4)

Andere Bezeichnung: PKP4

Hintergrund:

Synonyms: PKP4; Plakophilin-4; p0071

Background: Armadillo-like proteins are characterized by a series of armadillo repeats, first defined in the Drosophila 'armadillo' gene product, that are typically 42 to 45 amino acids in length. These proteins can be divided into subfamilies based on their number of repeats, their overall sequence similarity, and the dispersion of the repeats throughout their sequences. Members of the p120(ctn)/plakophilin subfamily of Armadillo-like proteins, including CTNND1, CTNND2, PKP1, PKP2, PKP4, and ARVCF. PKP4 may be a component of desmosomal plaque and other adhesion plaques and is thought to be involved in regulating junctional plaque organization and cadherin function. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2015],

Gene Name: PKP4

Protein Name: Plakophilin-4

Molekulargewicht: 134 kDa

Gen-ID: 604276

UniProt: Q99569

Pathways: Cell-Cell Junction Organization