SLC22A5 Antikörper (AA 300-349)

Produktnummer ABIN1451421

Der Kaninchen Polyklonal anti-SLC22A5 Antikörper (ABIN1451421) detektiert spezifisch SLC22A5 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für SLC22A5 Antikörper (AA 300-349) (ABIN1451421)

Target: SLC22A5 (Solute Carrier Family 22 Member 5 (SLC22A5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC22A5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SLC22A5 Antikörper

Bindungsspezifität: AA 300-349

Verwendungszweck: OCTN2 Antibody

Spezifität: OCTN2 Polyclonal Antibody detects endogenous levels of OCTN2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human SLC22A5. AA range:300-349

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu SLC22A5

Target: SLC22A5 (Solute Carrier Family 22 Member 5 (SLC22A5))

Andere Bezeichnung: SLC22A5

Hintergrund:

Synonyms: SLC22A5, OCTN2, Solute carrier family 22 member 5, High-affinity sodium-dependent carnitine cotransporter, Organic cation/carnitine transporter 2

Background: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015],

Gene Name: SLC22A5

Protein Name: Solute carrier family 22 member 5

Molekulargewicht: 62 kDa

Gen-ID: 6584

OMIM: 212140

UniProt: O76082