GLRB Antikörper (AA 211-260)

Produktnummer ABIN1451271

Der Kaninchen Polyklonal anti-GLRB Antikörper (ABIN1451271) detektiert spezifisch GLRB in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für GLRB Antikörper (AA 211-260) (ABIN1451271)

Target: GLRB (Glycine Receptor, beta (GLRB))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLRB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GLRB Antikörper

Bindungsspezifität: AA 211-260

Verwendungszweck: GlyRβ Antibody

Spezifität: GlyRβ Polyclonal Antibody detects endogenous levels of GlyRβ protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human GLRB. AA range:211-260

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu GLRB

Target: GLRB (Glycine Receptor, beta (GLRB))

Andere Bezeichnung: GLRB

Hintergrund:

Synonyms: GLRB, Glycine receptor subunit beta, Glycine receptor 58 kDa subunit

Background: This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],

Gene Name: GLRB

Protein Name: Glycine receptor subunit beta

Molekulargewicht: 56 kDa

Gen-ID: 2743

OMIM: 138492

UniProt: P48167