RAD18 Antikörper (AA 301-350)

Produktnummer ABIN1451241

Der Kaninchen Polyklonal anti-RAD18 Antikörper (ABIN1451241) detektiert spezifisch RAD18 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Ratte.

Kurzübersicht für RAD18 Antikörper (AA 301-350) (ABIN1451241)

Target: RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-RAD18 Antikörper

Bindungsspezifität: AA 301-350

Verwendungszweck: Rad18 Antibody

Spezifität: Rad18 Polyclonal Antibody detects endogenous levels of Rad18 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human RAD18. AA range:301-350

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu RAD18

Target: RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

Andere Bezeichnung: RAD18

Hintergrund:

Synonyms: RAD18, RNF73, E3 ubiquitin-protein ligase RAD18, Postreplication repair protein RAD18, hHR18, hRAD18, RING finger protein 73

Background: The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq, Jul 2008],

Gene Name: RAD18

Protein Name: E3 ubiquitin-protein ligase RAD18

Molekulargewicht: 56 kDa

Gen-ID: 56852

OMIM: 605256

UniProt: Q9NS91