Manic Fringe Antikörper (AA 61-110)

Produktnummer ABIN1451061

Der Kaninchen Polyklonal anti-Manic Fringe Antikörper (ABIN1451061) detektiert spezifisch Manic Fringe in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Manic Fringe Antikörper (AA 61-110) (ABIN1451061)

Target: Manic Fringe (MFNG) (MFNG)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Manic Fringe Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Manic Fringe Antikörper

Bindungsspezifität: AA 61-110

Verwendungszweck: Manic Fringe Antibody

Spezifität: Manic Fringe Polyclonal Antibody detects endogenous levels of Manic Fringe protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human MFNG. AA range:61-110

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Manic Fringe

Target: Manic Fringe (MFNG) (MFNG)

Andere Bezeichnung: MFNG

Hintergrund:

Synonyms: MFNG, Beta-1, 3-N-acetylglucosaminyltransferase manic fringe, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Background: This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. [provided by RefSeq, Oct 2009],

Gene Name: MFNG

Protein Name: Beta-1,3-N-acetylglucosaminyltransferase manic fringe

Molekulargewicht: 36 kDa

Gen-ID: 4242

OMIM: 602577

UniProt: O00587

Pathways: Notch Signalweg