TROVE2 Antikörper (AA 311-360)

Produktnummer ABIN1450995

Der Kaninchen Polyklonal anti-TROVE2 Antikörper (ABIN1450995) detektiert spezifisch TROVE2 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für TROVE2 Antikörper (AA 311-360) (ABIN1450995)

Target: TROVE2 (TROVE Domain Family, Member 2 (TROVE2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TROVE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TROVE2 Antikörper

Bindungsspezifität: AA 311-360

Verwendungszweck: RO60 Antibody

Spezifität: RO60 Polyclonal Antibody detects endogenous levels of RO60 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human TROVE2. AA range:311-360

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu TROVE2

Target: TROVE2 (TROVE Domain Family, Member 2 (TROVE2))

Andere Bezeichnung: TROVE2

Hintergrund:

Synonyms: TROVE2, RO60, SSA2, 60 kDa SS-A/Ro ribonucleoprotein, 60 kDa Ro protein, 60 kDa ribonucleoprotein Ro, RoRNP, Ro 60 kDa autoantigen, Sjoegren syndrome antigen A2, Sjoegren syndrome type A antigen, SS-A, TROVE domain family member 2

Background: disease:Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that react with the normal cellular SSA2 protein as if this antigen was foreign.,function:RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the Ro 60 kDa family.,similarity:Contains 1 TROVE domain.,subunit:Found in a complex with PUF60 and Y5 RNA. Interacts with RIP11.,

Gene Name: TROVE2

Protein Name: 60 kDa SS-A/Ro ribonucleoprotein

Molekulargewicht: 60 kDa

Gen-ID: 6738

OMIM: 600063

UniProt: P10155