IL17RA Antikörper (AA 141-190)

Produktnummer ABIN1450932

Der Kaninchen Polyklonal anti-IL17RA Antikörper (ABIN1450932) detektiert spezifisch IL17RA in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für IL17RA Antikörper (AA 141-190) (ABIN1450932)

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL17RA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-IL17RA Antikörper

Bindungsspezifität: AA 141-190

Verwendungszweck: IL-17Rα Antibody

Spezifität: IL-17Rα Polyclonal Antibody detects endogenous levels of IL-17Rα protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human IL17RA. AA range:141-190

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu IL17RA

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Andere Bezeichnung: IL17RA

Hintergrund:

Synonyms: IL17RA, IL17R, Interleukin-17 receptor A, IL-17 receptor A, IL-17RA, CDw217, CD antigen CD217

Background: Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014],

Gene Name: IL17RA

Protein Name: Interleukin-17 receptor A

Molekulargewicht: 96 kDa

Gen-ID: 23765

OMIM: 605461

UniProt: Q96F46

Pathways: SARS-CoV-2 Protein Interaktom