GTF3C4 Antikörper (AA 611-660)

Produktnummer ABIN1450890

Der Kaninchen Polyklonal anti-GTF3C4 Antikörper (ABIN1450890) detektiert spezifisch GTF3C4 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für GTF3C4 Antikörper (AA 611-660) (ABIN1450890)

Target: GTF3C4 (General Transcription Factor IIIC, Polypeptide 4 (GTF3C4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTF3C4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GTF3C4 Antikörper

Bindungsspezifität: AA 611-660

Verwendungszweck: TFIIIC90 Antibody

Spezifität: TFIIIC90 Polyclonal Antibody detects endogenous levels of TFIIIC90 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human TF3C4. AA range:611-660

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu GTF3C4

Target: GTF3C4 (General Transcription Factor IIIC, Polypeptide 4 (GTF3C4))

Hintergrund:

Synonyms: GTF3C4, General transcription factor 3C polypeptide 4, TF3C-delta, Transcription factor IIIC 90 kDa subunit, TFIIIC 90 kDa subunit, TFIIIC90, Transcription factor IIIC subunit delta

Background: catalytic activity:Acetyl-CoA + histone = CoA + acetylhistone.,function:Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the TFIIIC subunit 4 family.,subunit:Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6. Interacts with BRF1, GTF3C1, GTF3C2, GTF3C5, GTF3C6, POLR3C and POLR3F.,

Gene Name: GTF3C4

Protein Name: General transcription factor 3C polypeptide 4

Molekulargewicht: 92 kDa

Gen-ID: 9329

OMIM: 604892

UniProt: Q9UKN8