MDS1 Antikörper (AA 1-50)

Produktnummer ABIN1450839

Der Kaninchen Polyklonal anti-MDS1 Antikörper (ABIN1450839) detektiert spezifisch MDS1 in WB, ELISA, IF und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für MDS1 Antikörper (AA 1-50) (ABIN1450839)

Target: MDS1 (Myelodysplasia Syndrome 1 (MDS1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MDS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Produktdetails anti-MDS1 Antikörper

Bindungsspezifität: AA 1-50

Verwendungszweck: PRDM3 Antibody

Spezifität: PRDM3 Polyclonal Antibody detects endogenous levels of PRDM3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human MECOM. AA range:1-50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu MDS1

Target: MDS1 (Myelodysplasia Syndrome 1 (MDS1))

Andere Bezeichnung: Myelodysplasia Syndrome 1

Hintergrund:

Synonyms: MECOM, MDS1, MDS1 and EVI1 complex locus protein MDS1, Myelodysplasia syndrome 1 protein, Myelodysplasia syndrome-associated protein 1

Background: The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011],

Gene Name: MECOM

Protein Name: MDS1 and EVI1 complex locus protein MDS1

Molekulargewicht: 18 kDa

Gen-ID: 4197

OMIM: 600049

UniProt: Q13465