SIN3B Antikörper (AA 221-270)

Produktnummer ABIN1450803

Der Kaninchen Polyklonal anti-SIN3B Antikörper (ABIN1450803) detektiert spezifisch SIN3B in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für SIN3B Antikörper (AA 221-270) (ABIN1450803)

Target: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIN3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-SIN3B Antikörper

Bindungsspezifität: AA 221-270

Verwendungszweck: Sin3B Antibody

Spezifität: Sin3B Polyclonal Antibody detects endogenous levels of Sin3B protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human SIN3B. AA range:221-270

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu SIN3B

Target: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Andere Bezeichnung: SIN3B

Hintergrund:

Synonyms: SIN3B, KIAA0700, Paired amphipathic helix protein Sin3b, Histone deacetylase complex subunit Sin3b, Transcriptional corepressor Sin3b

Background: function:Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.,similarity:Contains 3 PAH (paired amphipathic helix) repeats.,subunit:Interacts with FOXK1/MNF, MXI, MAD, NCOR1 and SAP30. Interaction with SDS3 enhances the interaction with HDAC1 to form a complex. Interacts with MAD3, MAD4, MAEL, REST and SETDB1 (By similarity). Interacts with HCFC1.,

Gene Name: SIN3B

Protein Name: Paired amphipathic helix protein Sin3b

Molekulargewicht: 133 kDa

Gen-ID: 23309

OMIM: 607777

UniProt: O75182