VAV3 Antikörper (AA 139-188)

Produktnummer ABIN1450791

Der Kaninchen Polyklonal anti-VAV3 Antikörper (ABIN1450791) detektiert spezifisch VAV3 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für VAV3 Antikörper (AA 139-188) (ABIN1450791)

Target: VAV3 (Vav 3 Oncogene (VAV3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VAV3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-VAV3 Antikörper

Bindungsspezifität: AA 139-188

Verwendungszweck: Vav3 Antibody

Spezifität: Vav3 Polyclonal Antibody detects endogenous levels of Vav3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human VAV3. AA range:139-188

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu VAV3

Target: VAV3 (Vav 3 Oncogene (VAV3))

Andere Bezeichnung: VAV3

Hintergrund:

Synonyms: VAV3, Guanine nucleotide exchange factor VAV3, VAV-3

Background: This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

Gene Name: VAV3

Protein Name: Guanine nucleotide exchange factor VAV3

Molekulargewicht: 97 kDa

Gen-ID: 10451

OMIM: 605541

UniProt: Q9UKW4

Pathways: Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung