SNCA Antikörper (pTyr125)

Produktnummer ABIN1450389

Dieses Anti-SNCA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SNCA in ELISA und IHC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für SNCA Antikörper (pTyr125) (ABIN1450389)

Target: SNCA (Synuclein, alpha (SNCA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNCA Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-SNCA Antikörper

Bindungsspezifität: AA 91-140, pTyr125

Spezifität:

Synuclein-alpha (Phospho-Tyr125) Antibody detects endogenous levels of Synuclein-alpha only when phosphorylated at Tyr125.

PhosphorylationH:Y125, M:Y125, R:Y125

Aufreinigung: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Immunogen: The antiserum was produced against synthesized peptide derived from human Synuclein-alpha around the phosphorylation site of Tyr125.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC: 1:50~1:100 ELISA: 1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable at -20°C for at least 1 year.

Details zu SNCA

Target: SNCA (Synuclein, alpha (SNCA))

Andere Bezeichnung: Synuclein-alpha

Hintergrund:

Synonyms: Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP, SNCA, NACP, PARK1

NCBI Gene Symbol: SNCA

Molekulargewicht: 14 kDa

Gen-ID: 6622

OMIM: 127750

UniProt: P37840

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity