GFRA1 Antikörper

Produktnummer ABIN1450224

Dieses Anti-GFRA1-Antikörper ist ein Huhn Polyklonal-Antikörper zur Detektion von GFRA1 in WB, ELISA und IF. Geeignet für Human.

Kurzübersicht für GFRA1 Antikörper (ABIN1450224)

Target: GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

Reaktivität: Human

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser GFRA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-GFRA1 Antikörper

Spezifität: Glial cell line-derived neurotrophic factor (GDNF) andneurturin (NTN) are two structurally related, potent neurotrophic factors thatplay key roles in the control of neuron survival and differentiation. The GFRa-1is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediatesactivation of the RET tyrosine kinase receptor (www.ncbi.nlm.nih.gov/gene/2674)

Produktmerkmale: Mono- and polyclonal antibodies to human growth factors and neural growth factor receptors.

Aufreinigung: GFRa-1 affinity purified

Isotyp: IgY

Anwendungsinformationen

Applikationshinweise: Westernimmunoblotting, recommended dilution 1:5 000 to 1:10 000, ELISA: 1:80 000 to160 000,IF 1:1000 to 1:2000. Polyclonal antibody working titer has to be established practically for each particularantigen and assay format

Kommentare:

Synonym: RET ligand 1, TGF-beta related neurotrophic factorreceptor 1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml

Buffer: Concentrated ammonium sulphate in PBS pH 7.4

Handhabung: As product is (NH4)2SO4 precipitate, mix well by pipetting or vortexing prior use

Lagerung: 4 °C

Informationen zur Lagerung: This product is shipped in non-frozen liquid form in ambient conditions

Details zu GFRA1

Target: GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

Andere Bezeichnung: GFRa-1

Hintergrund: Recombinant His-tagged human GFRa-1 protein producedusing CHO-based cell line. For production of hGFRa-1, glycosylphosphatidyl-inositol GPI-anchor was removedand protein was secreted to the cell culture supernatant. Protein was purifiedby Ni-affinity chromatography following gel-filtration from cell culturesupernatant

UniProt: P56159