IRF2BP2 Antikörper (C-Term)

Produktnummer ABIN1450118

Der Kaninchen Polyklonal Anti-IRF2BP2-Antikörper wurde für WB, IF und EIA validiert. Er ist geeignet, IRF2BP2 in Proben von Human und Maus zu detektieren.

Kurzübersicht für IRF2BP2 Antikörper (C-Term) (ABIN1450118)

Target: IRF2BP2 (Interferon Regulatory Factor 2 Binding Protein 2 (IRF2BP2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF2BP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-IRF2BP2 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid synthetic peptide near the carboxy terminus of Human IRF2BP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IRF2BP2

Target: IRF2BP2 (Interferon Regulatory Factor 2 Binding Protein 2 (IRF2BP2))

Andere Bezeichnung: IRF2BP2

Hintergrund: IRF2BP2, like the related protein IRF2BP1, is a co-repressor that interacts specifically with the C-terminal repression domain of Interferon Regulatory Factor 2 (IRF2). IRF2BP2 is a direct target gene of p53 and is involved in cell survival during the p53 stress response, able to impede the p53-mediated transactivation of p21 and Bax. IRF2BP2 is also a co-factor of VGLL4 and is required to induce the expression of vascular endothelial growth factor A (VEGF-A) in muscle. It is normally found in the nucleus of skeletal muscle and cardiac cells, but can be found in the cytoplasm during skeletal muscle differentiation.Synonyms: IRF-2-binding protein 2, IRF-2BP2, Interferon regulatory factor 2-binding protein 2

Gen-ID: 359948

NCBI Accession: NP_892017