SIPA1 Antikörper (N-Term)

Produktnummer ABIN1450109

Der Kaninchen Polyklonal Anti-SIPA1-Antikörper wurde für WB, IF und EIA validiert. Er ist geeignet, SIPA1 in Proben von Human zu detektieren.

Kurzübersicht für SIPA1 Antikörper (N-Term) (ABIN1450109)

Target: SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIPA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-SIPA1 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid synthetic peptide from near the amino terminus of human SIPA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SIPA1

Target: SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))

Andere Bezeichnung: SIPA1 / SPA1

Hintergrund: Signal-induced proliferation 1 (SIPA1) is a member of the SIPA1 family of RapGAPs, a family of mitogen-induced GTPase activating proteins. SIPA1 exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. When abnormally or prematurely expressed, SIPA1 may also hamper mitogen-induced cell cycle progression and may increase metastases in human cancers.Synonyms: GTPase-activating protein Spa-1, Signal-induced proliferation-associated protein 1, Sipa-1, Spa-1, p130 SPA-1

Gen-ID: 6494

Pathways: Response to Water Deprivation