CHD7 Antikörper (N-Term)

Produktnummer ABIN1450043

Der Kaninchen Polyklonal anti-CHD7 Antikörper wird verwendet zum Nachweis von CHD7 in Proben von Human und Maus. Er wurde validiert für WB, IHC (p), IF und EIA.

Kurzübersicht für CHD7 Antikörper (N-Term) (ABIN1450043)

Target: CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHD7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-CHD7 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: CHD7 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CHD7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CHD7

Target: CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))

Andere Bezeichnung: CHD7

Hintergrund: CHD proteins belong to a superfamily of proteins of ATP-dependent chromatin remodeling enzymes that have a unique combination of functional domains, including two N-terminal chromodomains, a SNF2-like ATPase/helicase domain and a DNA-binding domain. These proteins are thought to play a role in early embryonic development by affecting chromatin structure and gene expression. Mutations in one member of this family, CHD7, result in CHARGE syndrome. It colocalizes with embryonic stem (ES) cell master regulators OCT4/POU5F1, SOX2, and NANOG and is thought to modulate ES-specific gene transcription. Together with SOX2, CHD7 has been suggested to also regulate several human disease genes.Synonyms: ATP-dependent helicase CHD7, CHD-7, Chromodomain-helicase-DNA-binding protein 7, KIAA1416

Gen-ID: 55636

UniProt: Q9P2D1

Pathways: Sensory Perception of Sound, Chromatin Binding