Der Kaninchen Polyklonal Anti-KCNK13-Antikörper wurde für WB, IF, IHC (p) und EIA validiert. Er ist geeignet, KCNK13 in Proben von Human, Maus und Ratte zu detektieren.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1.0 mg/mL
Buffer
PBS containing 0.02 % Sodium Azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
KCNK13
(Potassium Channel Subfamily K Member 13 (KCNK13))
Andere Bezeichnung
KCNK13
Hintergrund
The closely related proteins KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK13 is expressed mainly in the brain, but is also observed in kidneys. KCNK13 has been suggested to be a candidate for the Cs+-permeable K+ channel activated by GABA(B) receptors.Synonyms: KCNK13, Potassium channel subfamily K member 13, THIK-1, Tandem pore domain halothane-inhibited potassium channel 1