BRN2 antikoerper, N-Oct3 antikoerper, OCT7 antikoerper, OTF-7 antikoerper, OTF7 antikoerper, POUF3 antikoerper, brn-2 antikoerper, oct-7 antikoerper, XlPOU3 antikoerper, pou3f2 antikoerper, pou3f2-A antikoerper, pou3f4 antikoerper, 9430075J19Rik antikoerper, A230098E07Rik antikoerper, Brn-2 antikoerper, Brn2 antikoerper, Otf7 antikoerper, XLPOU3b antikoerper, pou47 antikoerper, zp47 antikoerper, zp47pou antikoerper, brn-1.2 antikoerper, brn1.2 antikoerper, id:ibd5088 antikoerper, POU class 3 homeobox 2 antikoerper, POU class 3 homeobox 2 L homeolog antikoerper, POU domain, class 3, transcription factor 2 antikoerper, POU class 3 homeobox 2 S homeolog antikoerper, POU class 3 homeobox 2b antikoerper, POU class 3 homeobox 2a antikoerper, POU3F2 antikoerper, pou3f2.L antikoerper, Pou3f2 antikoerper, pou3f2.S antikoerper, pou3f2b antikoerper, pou3f2a antikoerper
Hintergrund
POU3F2, also commonly known as brain-2, is a member of a family of POU domain genes expressed in mouse brain and is thought to be involved in the development of the neocortex and establishment of neural cell lineage (1,2). Recent studies suggest that POU3F2 may be involved with the development of neurodegenerative diseases as well as tumor development and proliferation. Along with the neural-lineage-specific transcription factors ASCL1 and MYT1L, POU3F2 can convert fibroblasts to functional neurons in vitro, a form of artificial stem cells termed induced neuronal (iN) cells, suggesting that these cells may be useful in the treatment of neurodegenerative diseases.Synonyms: BRN2, Brain-2, Brain-specific homeobox/POU domain protein 2, Brn-2, Nervous system-specific octamer-binding transcription factor N-Oct-3, OCT7, OTF-7, OTF7, Oct-7, Octamer-binding protein 7, Octamer-binding transcription factor 7, POU domain class 3 transcription factor 2