CASKIN1 Antikörper (Middle Region)
Kurzübersicht für CASKIN1 Antikörper (Middle Region) (ABIN1449997)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Aufreinigung
- Affinity chromatography purified via peptide column
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Immunogen
- A 17 amino acid synthetic peptide near the center of Human CASKIN1
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % Sodium Azide as preservative
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CASKIN1 (CASK Interacting Protein 1 (CASKIN1))
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Andere Bezeichnung
- CASKIN1
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Hintergrund
- Calcium/calmodulin-dependent serine protein kinase (CASK) is a conserved multi-domain scaffolding protein involved in brain development, synapse formation, and establishment of cell polarity. CASKINs (CASK interacting proteins) interact with CASK and is thought to play a role in CASK function, specifically by coupling CASK to distinct downstream effectors. CASKIN1 is a multidomain protein containing six N-terminal ankyrin repeats, one SH3 domain, and two sterile alpha motif domains followed by a long proline-rich sequence and a short conserved C-terminal domain. CASKIN1 coassembles with CASK on the cytoplasmic tail of neurexin 1, suggesting that CASKIN and CASK coat the cytoplasmic tails of neurexins and other cell-surface proteins.Synonyms: ANKS5A, CASK interacting protein 1, Caskin-1
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Molekulargewicht
- 157 kDa
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Gen-ID
- 57524
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NCBI Accession
- NP_065815
Target
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