CBX4 Antikörper (N-Term)
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- Target Alle CBX4 Antikörper anzeigen
- CBX4 (Chromobox Homolog 4 (CBX4))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CBX4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- A 17 amino acid synthetic peptide near the amino terminus of Human CBX4
- Isotyp
- IgG
- Top Product
- Discover our top product CBX4 Primärantikörper
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anti-Chromobox Homolog 4 (CBX4) (AA 397-514) antibody
CBX4 Reaktivität: Human WB, ELISA, IHC, ICC, FACS Wirt: Maus Monoclonal 6C5G3 unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 1-160) antibodyCBX4 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 80-110), (N-Term) antibodyCBX4 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB2931 unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 401-560) antibodyCBX4 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 401-500) antibodyCBX4 Reaktivität: Human, Maus WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 410-437), (C-Term) antibodyCBX4 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB2934 unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 1-290) antibodyCBX4 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 401-560) antibodyCBX4 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (N-Term) antibodyCBX4 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 150-200) antibodyCBX4 Reaktivität: Human, Maus, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Schwein IHC, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- CBX4 (Chromobox Homolog 4 (CBX4))
- Andere Bezeichnung
- CBX4 / PC2 (CBX4 Produkte)
- Synonyme
- MPc2 antikoerper, PC2 antikoerper, NBP16 antikoerper, XPolycomb antikoerper, cbx4-a antikoerper, im:6911625 antikoerper, zgc:158588 antikoerper, chromobox 4 antikoerper, chromobox 4 S homeolog antikoerper, chromobox homolog 4 antikoerper, chromobox homolog 4 (Pc class homolog, Drosophila) antikoerper, CBX4 antikoerper, Cbx4 antikoerper, cbx4.S antikoerper, cbx4 antikoerper
- Hintergrund
- Polycomb group (PcG) proteins are chromatin-associated proteins which are important for embryonic and adult stem cell self-renewal and maintenance. At least two distinct human PcG complexes have been identified. Polycomb repressive complex I (PRC1) contains CBX4/Pc2, HPH1 and RING domain-containing proteins (RING1, RING2 and BMI1). CBX4 (Chromobox protein homolog 4 or PC2), which functions as a transcriptional suppressor, is a candidate of KyoT2-binding proteins. It is a E3 SUMO-protein ligase which facilitates SUMO1 conjugation. Depletion of CBX4 results in decreased cellular resistance to ionizing radiation. CBX4 is directly involved in the cellular response to DNA damage.Synonyms: Chromobox protein homolog 4, E3 SUMO-protein ligase CBX4, Polycomb 2 homolog
- Molekulargewicht
- 62 kDa
- Gen-ID
- 8535
- NCBI Accession
- NP_003646
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